News
Our Degree Programs
Establishment
Language of instruction
French, English
Teaching content
Biology
Training officer(s)
S.DUPONT-WARGNIEZ
Stakeholder(s)
S.DUPONT-WARGNIEZ
Présentation
Goal
To acertain patterns of inheritance based on the study of pedigrees
To understand principles and possible uses of basic molecular genetics tools.
To emphasize the rich history of genetics
To understand principles and possible uses of basic molecular genetics tools.
To emphasize the rich history of genetics
Presentation
1st part : Mendelian genetics and its extensions
Chapter 1: Mendel laws
Chapter 2: Elements of cytology (mitosis, meiosis, gamete formation)
Chapter 3: The chromosome theory of inheritance
Chapter 4: Exceptions to the Mendel laws (codominance, epistasis ...)
Chapter 5: Intra chromosomal recombination (factorial linkage and recombination, chromatid and tetrad analysis)
Chapter 6: Gene mapping
TD: exercises
2nd part : Molecular genetics
Chapter 7: From chromosomal to molecular heredity
Chapter 8: The genome of eukaryotic cells (DNA structure, gene structure, extranuclear DNA)
Chapter 9: DNA replication, and repair mechanisms
Chapter 10: From genotype to phenotype (transcription, maturation, translation, mutations and polymorphisms)
Chapter 11: Genetics of bacteria
Chapter 12: Regulation of gene expression
TD: tools used in genetic engineering, and exercises : nucleic acid extraction, PCR, electrophoresis, enzymatic tools, Southern blot, sequencing, DNA chips, molecular cloning. GMO
Chapter 1: Mendel laws
Chapter 2: Elements of cytology (mitosis, meiosis, gamete formation)
Chapter 3: The chromosome theory of inheritance
Chapter 4: Exceptions to the Mendel laws (codominance, epistasis ...)
Chapter 5: Intra chromosomal recombination (factorial linkage and recombination, chromatid and tetrad analysis)
Chapter 6: Gene mapping
TD: exercises
2nd part : Molecular genetics
Chapter 7: From chromosomal to molecular heredity
Chapter 8: The genome of eukaryotic cells (DNA structure, gene structure, extranuclear DNA)
Chapter 9: DNA replication, and repair mechanisms
Chapter 10: From genotype to phenotype (transcription, maturation, translation, mutations and polymorphisms)
Chapter 11: Genetics of bacteria
Chapter 12: Regulation of gene expression
TD: tools used in genetic engineering, and exercises : nucleic acid extraction, PCR, electrophoresis, enzymatic tools, Southern blot, sequencing, DNA chips, molecular cloning. GMO
Modalités
Organization
| Type | Amount of time | Comment | |
|---|---|---|---|
| Independent study | |||
| Estimated personal study time | 80,00 | ||
| Face to face | |||
| Lecture | 32,00 | ||
| Seminar | 22,00 | ||
| Overall student workload | 134,00 | ||
Evaluation
| Control type | Duration | Amount | Weighting |
|---|---|---|---|
| Continuous assessment | |||
| Final written exam | 2,00 | 1 | 37,78 |
| Written exam | 2,00 | 2 | 62,22 |
| TOTAL | 99,00 | ||
Ressources
Bibliography
Analyse génétique moderne. - Griffiths A., Gelbart W., Miller J., Lewontin R.
DeBoeck Université. 2001
Génétique – Des caractères aux gènes - Bernard J.J.Collection synapses. Hachette 1993
Principes de biologie moléculaire en biologie clinique - Ameziane N., Bogard M., Lamoril J.Elsevier SAS 2006