Establishment
Language of instruction
French, English
This course occurs in the following program(s)
Licence Sciences de la Vie - Parcours Biotechnologies
- Crédits ECTS:
Training officer(s)
Valerie CONSEIL
Présentation
Prerequisite
B102, B202, B402.
Goal
Presentation of the main pathways of intermediate metabolism (catabolism and anabolism) and their regulation.
Presentation
METABOLISM
I. OVERVIEW
II. BIOENERGETICS
1. Revision of thermodynamics (application to biological systems)
2. Variation in free energy and redox potential
3. ATP - the currency of energy exchange
III. LIPID METABOLISM
A. Fatty acid metabolism
1. Redistribution of dietary lipids and adipose tissue
2. Catabolism of fatty acids: beta-oxidation of fatty acids
3. Anabolism of fatty acids: synthesis of fatty acids
B. Biosynthesis of glycerol
1. Anabolism of triglycerides
2. Anabolism of phospheroglycerides
C. Metabolism of cholesterol
IV. CARBOHYDRATE METABOLISM
A. Glycogen metabolism
1. Glycogen catabolism
2. Glycogen anabolism - glycogenesis
B. Regulation of glycogen metabolism
1. Glycolosis
2. Neoglucogenesis
3. Pentose phosphate pathway
V. CELLULAR ENERGETICS
A. The citric acid cycle
B. The respiratory chain and oxidation phosphorylation
VI. AMINO ACID METABOLISM
A. Catabolism of nitrogen in amino acids
B. Catabolism of carbon stem of amino acids
C. Synthesis of amino acids
I. OVERVIEW
II. BIOENERGETICS
1. Revision of thermodynamics (application to biological systems)
2. Variation in free energy and redox potential
3. ATP - the currency of energy exchange
III. LIPID METABOLISM
A. Fatty acid metabolism
1. Redistribution of dietary lipids and adipose tissue
2. Catabolism of fatty acids: beta-oxidation of fatty acids
3. Anabolism of fatty acids: synthesis of fatty acids
B. Biosynthesis of glycerol
1. Anabolism of triglycerides
2. Anabolism of phospheroglycerides
C. Metabolism of cholesterol
IV. CARBOHYDRATE METABOLISM
A. Glycogen metabolism
1. Glycogen catabolism
2. Glycogen anabolism - glycogenesis
B. Regulation of glycogen metabolism
1. Glycolosis
2. Neoglucogenesis
3. Pentose phosphate pathway
V. CELLULAR ENERGETICS
A. The citric acid cycle
B. The respiratory chain and oxidation phosphorylation
VI. AMINO ACID METABOLISM
A. Catabolism of nitrogen in amino acids
B. Catabolism of carbon stem of amino acids
C. Synthesis of amino acids
Modalités
Evaluation